Nitric Oxide
In 1998 the Nobel prize in physiology was jointly awarded to three scientists, Robert F. Furchgott, Louis J. Ignarro, and Ferid Murad, for his or her discovery of nitric oxide (NO) as a signaling molecule in the cardiovascular system. The importance of NO's discovery can't be understated. What have been, ahead of its discovery in our body, considered an environmental pollutant is now known to be just about the most important molecules in our body. In Redox Signaling Molecules at the Nobel Prize Ceremony, Professor Sten Lindahl had this to say about the discovery: "Your discoveries concerning nitric oxide as a signaling molecule in the cardiovascular system, haven't only explained the working principle of an old important group of drugs, the nitrovasodilators, it has additionally opened new avenues for patient treatment and diagnoses of varied diseases. Your discoveries have lifted medical research into a new era."
What is it?
NO is a highly reactive gas that's naturally produced in the human body. It affects various physiological functions including circulation, inflammation, learning and memory, digestion, penile erection, and oxygen release in tissues from red blood cells. It is produced in your body through the conversion of L-arginine (an amino acid) by NO synthase. The process of aging decreases your body's ability to produce nitric oxide and as a result, many people lack in nitric oxide production. Lower production of Nitric Oxide that results from age is in charge of many ailments faced in modern society.
What does it do?
NO has a selection of physiological roles in your body, but its most significant role is in the relaxation of the smooth muscles in the artery (vasodilation). The opening of arteries allows for an increase of blood flow round the body. This increases the efficiency of which nutrients and molecules can travel to sites worth focusing on. Lower level of NO within the body as a result of age are responsible for a number of different diseases including: atherosclerosis, peripheral artery disease, stroke, hair loss, erection dysfunction, diabetes, and pain.
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